Inhibition of P2Y11R ameliorated TNF-α-induced degradation of extracellular matrix in human chondrocytic SW1353 cells

Osteoarthritis is a major global health burden. Joint destruction resulting from excessive degradation of type II collagen and aggrecan in the articular extracellular matrix by metalloproteinases and aggrecanases, respectively, is a major pathological hallmark of osteoarthritis. However, the exact m...

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Bibliographic Details
Published in:Am J Transl Res
Main Authors: Wang, Dawei, Lin, Nan, Tang, Yicun, Lu, Huading
Format: Artigo
Language:Inglês
Published: e-Century Publishing Corporation 2019
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511765/
https://ncbi.nlm.nih.gov/pubmed/31105822
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