Inhibition of P2Y11R ameliorated TNF-α-induced degradation of extracellular matrix in human chondrocytic SW1353 cells

Osteoarthritis is a major global health burden. Joint destruction resulting from excessive degradation of type II collagen and aggrecan in the articular extracellular matrix by metalloproteinases and aggrecanases, respectively, is a major pathological hallmark of osteoarthritis. However, the exact m...

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Bibliografiske detaljer
Udgivet i:Am J Transl Res
Main Authors: Wang, Dawei, Lin, Nan, Tang, Yicun, Lu, Huading
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2019
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511765/
https://ncbi.nlm.nih.gov/pubmed/31105822
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