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MicroRNA-495 enhances chondrocyte apoptosis, senescence and promotes the progression of osteoarthritis by targeting AKT1

Osteoarthritis (OA) is a common multifactorial degenerative articular disease among the aging population. The current investigation aimed to elucidate the function of microRNA-495 (miR-495) in the development of OA. We found that miR-495 was upregulated in the cartilage of OA patients. Transfection...

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Detalhes bibliográficos
Publicado no:Am J Transl Res
Main Authors: Zhao, Xingyu, Wang, Tiejun, Cai, Bo, Wang, Xiaoning, Feng, Wei, Han, Yu, Li, Dongsong, Li, Shuqiang, Liu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511756/
https://ncbi.nlm.nih.gov/pubmed/31105831
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