The structure of Trametes versicolor glutathione transferase Omega 3S bound to its conjugation product glutathionyl‐phenethylthiocarbamate reveals plasticity of its active site

Trametes versicolor glutathione transferase Omega 3S (TvGSTO3S) catalyzes the conjugation of isothiocyanates (ITC) with glutathione (GSH). Previously, this isoform was investigated in depth both biochemically and structurally. Structural analysis of complexes revealed the presence of a GSH binding s...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Schwartz, Mathieu, Perrot, Thomas, Morel‐Rouhier, Mélanie, Mulliert, Guillermo, Gelhaye, Eric, Didierjean, Claude, Favier, Frédérique
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Protein Structure Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511745/
https://ncbi.nlm.nih.gov/pubmed/30972861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3620
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