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Taking SCLC on a Bad LSD(1) Trip One NOTCH Further
Small cell lung cancer (SCLC) is an aggressive form of lung cancer for which therapeutic options are very limited. A new study (Augert et al. Sci. Signal. 2019;12: eaau2922) shows that inhibition of the LSD1 demethylase can induce derepression of NOTCH receptor genes and subsequent activation of the...
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| Publicado no: | Trends Mol Med |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6511648/ https://ncbi.nlm.nih.gov/pubmed/30852141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2019.02.009 |
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