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Generation of a CRISPR/Cas9-Based Vector Specific for Gene Manipulation in Leishmania major

BACKGROUND: Gene manipulation strategies including gene knockout and editing are becoming more sophisticated in terms of mechanism of action, efficacy and ease of use. In classical molecular methods of gene knockout, homologous arms are designed for induction of crossing over event in double strand...

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Bibliografski detalji
Izdano u:Iran J Parasitol
Glavni autori: SALEHI SANGANI, Ghodratollah, JAJARMI, Vahid, KHAMESIPOUR, Ali, MAHMOUDI, Mahmoud, FATA, Abdolmajid, MOHEBALI, Mehdi
Format: Artigo
Jezik:Inglês
Izdano: Tehran University of Medical Sciences 2019
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511583/
https://ncbi.nlm.nih.gov/pubmed/31123471
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