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CRISPR/Cas9 Mutagenesis in Phlebotomus papatasi: the Immune Deficiency Pathway Impacts Vector Competence for Leishmania major

Sand flies are the natural vectors for the Leishmania species that produce a spectrum of diseases in their mammalian hosts, including humans. Studies of sand fly/Leishmania interactions have been limited by the absence of genome editing techniques applicable to these insects. In this report, we adap...

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Detalhes bibliográficos
Publicado no:mBio
Principais autores: Louradour, Isabelle, Ghosh, Kashinath, Inbar, Ehud, Sacks, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6712399/
https://ncbi.nlm.nih.gov/pubmed/31455654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01941-19
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