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RNAi expression tuning, microfluidic screening, and genome recombineering for improved protein production in Saccharomyces cerevisiae

The cellular machinery that supports protein synthesis and secretion lies at the foundation of cell factory-centered protein production. Due to the complexity of such cellular machinery, the challenge in generating a superior cell factory is to fully exploit the production potential by finding benef...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Wang, Guokun, Björk, Sara M., Huang, Mingtao, Liu, Quanli, Campbell, Kate, Nielsen, Jens, Joensson, Haakan N., Petranovic, Dina
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511059/
https://ncbi.nlm.nih.gov/pubmed/31000602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1820561116
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