Hemidesmus indicus induces apoptosis via proteasome inhibition and generation of reactive oxygen species

Proteasome inhibition represents an important anticancer strategy. Here, we studied the mechanisms at the basis of the pro-apoptotic activity of the standardized decoction of Hemidesmus indicus, a plant evoking a complex anticancer activity, and explored its inhibition of proteasome activity in huma...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Turrini, Eleonora, Catanzaro, Elena, Ferruzzi, Lorenzo, Guerrini, Alessandra, Tacchini, Massimo, Sacchetti, Gianni, Paganetto, Guglielmo, Maffei, Francesca, Pellicioni, Valentina, Poli, Ferruccio, Hrelia, Patrizia, Mandrone, Manuela, Sestili, Piero, Brigotti, Maurizio, Fimognari, Carmela
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2019
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510901/
https://ncbi.nlm.nih.gov/pubmed/31076590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43609-5
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