Sulforaphane Potentiates RNA Damage Induced by Different Xenobiotics

BACKGROUND: The isothiocyanate sulforaphane (SFN) possesses interesting anticancer activities. However, recent studies reported that SFN promotes the formation of reactive oxygen species (ROS) as well as DNA breakage. METHODOLOGY/PRINCIPAL FINDINGS: We investigated whether SFN is able to damage RNA,...

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Detalhes bibliográficos
Main Authors: Fimognari, Carmela, Lenzi, Monia, Sestili, Piero, Turrini, Eleonora, Ferruzzi, Lorenzo, Hrelia, Patrizia, Cantelli-Forti, Giorgio
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3335137/
https://ncbi.nlm.nih.gov/pubmed/22539965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0035267
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