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Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury

Axonal degeneration occurs in various neurological diseases and traumatic nerve injury, and axonal regeneration is restricted by inhibitory factors in the central nervous system. Cyclin-dependent kinase 5 and glycogen synthase kinase 3β (GSK3β) are activated by one of those inhibitors, and collapsin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Kondo, Shunsuke, Takahashi, Kazuya, Kinoshita, Yuki, Nagai, Jun, Wakatsuki, Shuji, Araki, Toshiyuki, Goshima, Yoshio, Ohshima, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510754/
https://ncbi.nlm.nih.gov/pubmed/31076621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43658-w
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