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Efficacy of the novel CDK7 inhibitor QS1189 in mantle cell lymphoma

Mantle cell lymphoma (MCL) is typically an aggressive and rare form of non-Hodgkin lymphoma (NHL) with a poor prognosis despite recent advances in immunochemotherapy and targeted therapeutics against NHL. New therapeutic agents are needed for MCL. In this study, we generated a potent inhibitor of cy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Choi, Yun Jung, Kim, Dong Ha, Yoon, Dok Hyun, Suh, Cheolwon, Choi, Chang-Min, Lee, Jae Cheol, Hong, Jung Yong, Rho, Jin Kyung
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510728/
https://ncbi.nlm.nih.gov/pubmed/31076643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-43760-z
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