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STAT6 knockdown using multiple siRNA sequences inhibits proliferation and induces apoptosis of human colorectal and breast cancer cell lines

The transcription factor STAT6 is strongly expressed in various tumours and is most highly expressed in human malignant lymphomas and pancreatic, colorectal, prostate and breast cancers. STAT6 is associated with cancer cell proliferation, an increased malignancy and poor prognosis. Thus, techniques...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Salguero-Aranda, Carmen, Sancho-Mensat, Daniel, Canals-Lorente, Beatriz, Sultan, Sabena, Reginald, Ajan, Chapman, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510441/
https://ncbi.nlm.nih.gov/pubmed/31075146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207558
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