VKORC1 and Novel CYP2C9 Variation Predict Warfarin Response in Alaska Native and American Indian People

Alaska Native and American Indian (AN/AI) people have unique pharmacogene variation that may affect warfarin disposition and therapeutic response. We performed targeted genotyping for cytochrome P450 (CYP)2C9, vitamin K epoxide oxidase reductase complex subunit 1 (VKORC1), CYP4F2,CYP4F11, and gamma‐...

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Publicado en:Clin Transl Sci
Autores principales: Henderson, Lindsay M., Robinson, Renee F., Ray, Lily, Khan, Burhan A., Li, Tianran, Dillard, Denise A., Schilling, Brian D., Mosley, Mike, Janssen, Patricia L., Fohner, Alison E., Rettie, Allan E., Thummel, Kenneth E., Thornton, Timothy A., Veenstra, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510382/
https://ncbi.nlm.nih.gov/pubmed/30821933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12611
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