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Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle

Durable humoral immunity is dependent upon the generation of antigen-specific antibody titers, produced by non-proliferating bone marrow resident long-lived plasma cells (LLPC). Longevity is the hallmark of LLPC, but why and how they survive and function for years after antigen exposure is only begi...

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Pubblicato in:Front Immunol
Autori principali: Lightman, Shivana M., Utley, Adam, Lee, Kelvin P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510054/
https://ncbi.nlm.nih.gov/pubmed/31130955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00965
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