Lipoprotein(a) Particle Production as a Determinant of Plasma Lipoprotein(a) Concentration Across Varying Apolipoprotein(a) Isoform Sizes and Background Cholesterol‐Lowering Therapy

BACKGROUND: Elevated lipoprotein(a) (Lp(a)), a low‐density lipoprotein‐like particle bound to the polymorphic apolipoprotein(a) (apo(a)), may be causal for cardiovascular disease. However, the metabolism of Lp(a) in humans is poorly understood. METHODS AND RESULTS: We investigated the kinetics of Lp...

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Detalhes bibliográficos
Publicado no:J Am Heart Assoc
Main Authors: Chan, Dick C., Watts, Gerald F., Coll, Blai, Wasserman, Scott M., Marcovina, Santica M., Barrett, P. Hugh R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509712/
https://ncbi.nlm.nih.gov/pubmed/30897995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.011781
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