Impact of Apolipoprotein(a) Isoform Size on Lipoprotein(a) Lowering in the HPS2-THRIVE Study

BACKGROUND: Genetic studies have shown lipoprotein(a) (Lp[a]) to be an important causal risk factor for coronary disease. Apolipoprotein(a) isoform size is the chief determinant of Lp(a) levels, but its impact on the benefits of therapies that lower Lp(a) remains unclear. METHODS: HPS2-THRIVE (Heart...

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Detalhes bibliográficos
Publicado no:Circ Cardiovasc Genet
Main Authors: Parish, Sarah, Hopewell, Jemma C., Hill, Michael R., Marcovina, Santica, Valdes-Marquez, Elsa, Haynes, Richard, Offer, Alison, Pedersen, Terje R., Baigent, Colin, Collins, Rory, Landray, Martin, Armitage, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841847/
https://ncbi.nlm.nih.gov/pubmed/29449329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.001696
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