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Impact of Apolipoprotein(a) Isoform Size on Lipoprotein(a) Lowering in the HPS2-THRIVE Study

BACKGROUND: Genetic studies have shown lipoprotein(a) (Lp[a]) to be an important causal risk factor for coronary disease. Apolipoprotein(a) isoform size is the chief determinant of Lp(a) levels, but its impact on the benefits of therapies that lower Lp(a) remains unclear. METHODS: HPS2-THRIVE (Heart...

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Foilsithe in:Circ Cardiovasc Genet
Main Authors: Parish, Sarah, Hopewell, Jemma C., Hill, Michael R., Marcovina, Santica, Valdes-Marquez, Elsa, Haynes, Richard, Offer, Alison, Pedersen, Terje R., Baigent, Colin, Collins, Rory, Landray, Martin, Armitage, Jane
Formáid: Artigo
Teanga:Inglês
Foilsithe: Lippincott Williams & Wilkins 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5841847/
https://ncbi.nlm.nih.gov/pubmed/29449329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGEN.117.001696
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