DDR1 and MT1-MMP Expression Levels Are Determinant for Triggering BIK-Mediated Apoptosis by 3D Type I Collagen Matrix in Invasive Basal-Like Breast Carcinoma Cells

Type I collagen is the major adhesive component in breast interstitial stroma, which represents the first barrier against tumor cell invasion after basement-membrane degradation. Among cellular receptors, type I collagen is able to activate discoidin domain receptors DDR1 and DDR2. We have previousl...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Saby, Charles, Collin, Guillaume, Sinane, Maha, Buache, Emilie, Van Gulick, Laurence, Saltel, Frédéric, Maquoi, Erik, Morjani, Hamid
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509437/
https://ncbi.nlm.nih.gov/pubmed/31130862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00462
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