Influenza “Trains” the Host for Enhanced Susceptibility to Secondary Bacterial Infection

We previously reported that the Toll-like receptor 4 (TLR4) antagonist Eritoran blocks acute lung injury (ALI) therapeutically in mouse and cotton rat models of influenza. However, secondary (2°) bacterial infection following influenza virus infection is associated with excess morbidity and mortalit...

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Publicat a:mBio
Autors principals: Shirey, Kari Ann, Perkins, Darren J., Lai, Wendy, Zhang, Wei, Fernando, Lurds R., Gusovsky, Fabian, Blanco, Jorge C. G., Vogel, Stefanie N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509193/
https://ncbi.nlm.nih.gov/pubmed/31064834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00810-19
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