Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway

Viral infections induce proinflammatory signaling cascades and inflammatory cytokine production, which is precisely regulated for host benefits. In the current study, we unravel a previously unappreciated role of nonmuscle myosin heavy chain IIA (NMHC-IIA) as a negative regulator in inflammatory res...

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Udgivet i:mBio
Main Authors: Liu, Yingqi, Li, Rui, Chen, Xin-xin, Zhi, Yubao, Deng, Ruiguang, Zhou, En-min, Qiao, Songlin, Zhang, Gaiping
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509187/
https://ncbi.nlm.nih.gov/pubmed/31064828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00574-19
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