Nontypeable Haemophilus influenzae Has Evolved Preferential Use of N-Acetylneuraminic Acid as a Host Adaptation

Nontypeable Haemophilus influenzae (NTHi) is a Gram-negative bacterial pathogen that is adapted exclusively to human hosts. NTHi utilizes sialic acid from the host as a carbon source and as a terminal sugar on the outer membrane glycolipid lipooligosaccharide (LOS). Sialic acid expressed on LOS is cr...

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Udgivet i:mBio
Main Authors: Ng, Preston S. K., Day, Christopher J., Atack, John M., Hartley-Tassell, Lauren E., Winter, Linda E., Marshanski, Tal, Padler-Karavani, Vered, Varki, Ajit, Barenkamp, Stephen J., Apicella, Michael A., Jennings, Michael P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509186/
https://ncbi.nlm.nih.gov/pubmed/31064827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00422-19
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