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A Tripartite Interaction Among the Calcium Channel α(1)- and β-Subunits and F-Actin Increases the Readily Releasable Pool of Vesicles and Its Recovery After Depletion

Neurotransmitter release is initiated by the influx of Ca(2+) via voltage-gated calcium channels. The accessory β-subunit (Ca(V)β) of these channels shapes synaptic transmission by associating with the pore-forming subunit (Ca(V)α(1)) and up-regulating presynaptic calcium currents. Besides Ca(V)α(1,...

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Publicat a:Front Cell Neurosci
Autors principals: Guzman, Gustavo A., Guzman, Raul E., Jordan, Nadine, Hidalgo, Patricia
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509170/
https://ncbi.nlm.nih.gov/pubmed/31130843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00125
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