Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism

Biological roles of obscurin and its close homolog Obsl1 (obscurin-like 1) have been enigmatic. While obscurin is highly expressed in striated muscles, Obsl1 is found ubiquitously. Accordingly, obscurin mutations have been linked to myopathies, whereas mutations in Obsl1 result in 3M-growth syndrome...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Commun Biol
Päätekijät: Blondelle, Jordan, Marrocco, Valeria, Clark, Madison, Desmond, Patrick, Myers, Stephanie, Nguyen, Jim, Wright, Matthew, Bremner, Shannon, Pierantozzi, Enrico, Ward, Samuel, Estève, Eric, Sorrentino, Vincenzo, Ghassemian, Majid, Lange, Stephan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509138/
https://ncbi.nlm.nih.gov/pubmed/31098411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0405-7
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia