Murine obscurin and Obsl1 have functionally redundant roles in sarcolemmal integrity, sarcoplasmic reticulum organization, and muscle metabolism

Biological roles of obscurin and its close homolog Obsl1 (obscurin-like 1) have been enigmatic. While obscurin is highly expressed in striated muscles, Obsl1 is found ubiquitously. Accordingly, obscurin mutations have been linked to myopathies, whereas mutations in Obsl1 result in 3M-growth syndrome...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Commun Biol
Main Authors: Blondelle, Jordan, Marrocco, Valeria, Clark, Madison, Desmond, Patrick, Myers, Stephanie, Nguyen, Jim, Wright, Matthew, Bremner, Shannon, Pierantozzi, Enrico, Ward, Samuel, Estève, Eric, Sorrentino, Vincenzo, Ghassemian, Majid, Lange, Stephan
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509138/
https://ncbi.nlm.nih.gov/pubmed/31098411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0405-7
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares