Colitis-induced Th17 cells increase the risk for severe subsequent Clostridium difficile infection

Clostridium difficile infection (CDI) is the number one hospital-acquired infection in the United States. CDI is more common and severe in inflammatory bowel disease patients. Here we studied the mechanism by which prior colitis exacerbates CDI. Mice were given Dextran Sulfate Sodium (DSS)-colitis,...

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Publicado en:Cell Host Microbe
Main Authors: Saleh, Mahmoud M., Frisbee, Alyse L., Leslie, Jhansi L., Buonomo, Erica L., Cowardin, Carrie A., Ma, Jennie Z., Simpson, Morgan E., Scully, Kenneth W., Abhyankar, Mayuresh M., Petri, William A.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6509008/
https://ncbi.nlm.nih.gov/pubmed/31003940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2019.03.003
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