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Inflammasome Activation Contributes to Interleukin-23 Production in Response to Clostridium difficile

Clostridium difficile is the most common hospital-acquired pathogen, causing antibiotic-associated diarrhea in over 250,000 patients annually in the United States. Disease is primarily mediated by toxins A and B, which induce potent proinflammatory signaling in host cells and can activate an ASC-con...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Cowardin, Carrie A., Kuehne, Sarah A., Buonomo, Erica L., Marie, Chelsea S., Minton, Nigel P., Petri, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4324312/
https://ncbi.nlm.nih.gov/pubmed/25626905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02386-14
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