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A65 HNF4A IS A KEY REGULATOR OF THE EPITHELIAL STEM CELL NICHE.
BACKGROUND: HNF4α is a transcriptional factor downregulated in intestinal bowel diseases (IBD). Epithelial deletion of HNF4α in the mouse intestine leads to spontaneous intestinal inflammation. Those observations suggest that HNF4α could play an important role in epithelial homeostasis. The intestin...
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| Publicat a: | J Can Assoc Gastroenterol |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6508239/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy009.065 |
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