PROTEASOME LEVELS AND ACTIVITY IN PREGNANCIES COMPLICATED BY SEVERE PREECLAMPSIA AND HELLP SYNDROME

Excessive accumulation of misfolded proteins was recently demonstrated in preeclampsia (PE). We examined levels and activity of circulatory proteasome and immunoproteasome (inflammatory subtype) in PE and HELLP syndrome. We analyzed samples from women with hypertensive pregnancy disorders (n=115), i...

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Опубликовано в: :Hypertension
Главные авторы: Berryman, Kathryn, Buhimschi, Catalin S., Zhao, Guomao, Axe, Michelle, Locke, Megan, Buhimschi, Irina A.
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508099/
https://ncbi.nlm.nih.gov/pubmed/31067191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12437
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