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PROTEASOME LEVELS AND ACTIVITY IN PREGNANCIES COMPLICATED BY SEVERE PREECLAMPSIA AND HELLP SYNDROME

Excessive accumulation of misfolded proteins was recently demonstrated in preeclampsia (PE). We examined levels and activity of circulatory proteasome and immunoproteasome (inflammatory subtype) in PE and HELLP syndrome. We analyzed samples from women with hypertensive pregnancy disorders (n=115), i...

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Bibliographic Details
Published in:Hypertension
Main Authors: Berryman, Kathryn, Buhimschi, Catalin S., Zhao, Guomao, Axe, Michelle, Locke, Megan, Buhimschi, Irina A.
Format: Artigo
Language:Inglês
Published: 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6508099/
https://ncbi.nlm.nih.gov/pubmed/31067191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.12437
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