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A276 INVESTIGATING THE ROLE OF TTC7A THROUGH ITS INTERACTION WITH UBR5 TO MAINTAIN CELL SURVIVAL

BACKGROUND: Patients with mutations in Tetratricopeptide Repeat Domain 7A (TTC7A) results in a severe and untreatable form of inflammatory bowel disease with the majority dying before 2 years of age. Pathological features of these patients include intestinal apoptosis and disrupted apicobasal polari...

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Publié dans:J Can Assoc Gastroenterol
Auteurs principaux: Dhingani, N, Guo, C, Warner, N, Murchie, R, Muise, A
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2018
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507826/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.277
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