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A99 SYSTEMIC DELIVERY OF AN INHIBITOR OF MITOCHONDRIAL FISSION REDUCES THE SEVRITY OF CHEMICALLY-INDUCED COLITIS IN MICE

BACKGROUND: Mitochondria exist as a dynamic network that is continually remodelling by the controlled processes of fission and fusion that are critical to cell health, regulating metabolic activity, proliferation and apoptosis. Excessive mitochondrial fission can be a feature of neurological and met...

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Veröffentlicht in:J Can Assoc Gastroenterol
Hauptverfasser: Mancini, N, Xu, W, Shearer, J, McKay, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507689/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.100
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