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A288 DISTINCT ROLES IN INNATE HOST DEFENSE AND SUSCEPTIBILITY TO COLONIC INJURY IN MUC2 MUCIN DEFICIENT AND SUFFICIENT MICROBIOTA

BACKGROUND: The intestinal epithelium is covered with a thick viscous MUC2 mucin bilayer that acts as a protective barrier and is the habitat for 10(14) microorganisms that form the microbiota. Even though disruption of colonic mucus and alterations in microbial composition are intimately linked to...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Leon-Coria, A, Moreau, F, Workentine, M, Surette, M, Chadee, K
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507653/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.289
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