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Colonic MUC2 mucin regulates the expression and antimicrobial activity of β-defensin 2

In this study we identified mechanisms at the colonic mucosa by which MUC2 mucin regulated the production of β-defensin in a proinflammatory milieu but functionally protected susceptible bacteria from its antimicrobial effects. The regulator role of MUC2 on production of β-defensin 2 in combination...

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Publicat a:Mucosal Immunol
Autors principals: Cobo, E R, Kissoon-Singh, V, Moreau, F, Chadee, K
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762903/
https://ncbi.nlm.nih.gov/pubmed/25921338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2015.27
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