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MUC2 Mucin and Butyrate Contribute to the Synthesis of the Antimicrobial Peptide Cathelicidin in Response to Entamoeba histolytica- and Dextran Sodium Sulfate-Induced Colitis

Embedded in the colonic mucus are cathelicidins, small cationic peptides secreted by colonic epithelial cells. Humans and mice have one cathelicidin-related antimicrobial peptide (CRAMP) each, LL-37/hCAP-18 and Cramp, respectively, with related structure and functions. Altered production of MUC2 muc...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Cobo, Eduardo R., Kissoon-Singh, Vanessa, Moreau, France, Holani, Ravi, Chadee, Kris
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328487/
https://ncbi.nlm.nih.gov/pubmed/28069814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00905-16
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