A102 THIOPURINE METABOLITE LEVEL MONITORING LEADS TO INDIVIDUALIZED AND OPTIMIZED THIOPURINE THERAPY IN ADULT INFLAMMATORY BOWEL DISEASE (IBD)

BACKGROUND: The thiopurine drugs (6-MP, azathioprine (AZA)) are purine anti-metabolites commonly used in IBD. About 55% of active IBD fail to respond to thiopurine weight based dosing. Studies suggest 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP) levels are better therapeutic targets than...

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Detalhes bibliográficos
Publicado no:J Can Assoc Gastroenterol
Main Authors: Zhu, J, Abraldes, J, Dieleman, L A, Huang, V, Kroeker, K I, Peerani, F, Wong, K, LeGatt, D, Fedorak, R, Halloran, B P
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Poster Presentations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507612/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.103
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