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A102 THIOPURINE METABOLITE LEVEL MONITORING LEADS TO INDIVIDUALIZED AND OPTIMIZED THIOPURINE THERAPY IN ADULT INFLAMMATORY BOWEL DISEASE (IBD)
BACKGROUND: The thiopurine drugs (6-MP, azathioprine (AZA)) are purine anti-metabolites commonly used in IBD. About 55% of active IBD fail to respond to thiopurine weight based dosing. Studies suggest 6-thioguanine (6-TG) and 6-methylmercaptopurine (6-MMP) levels are better therapeutic targets than...
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| Pubblicato in: | J Can Assoc Gastroenterol |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6507612/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jcag/gwy008.103 |
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