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Evaluating tofacitinib citrate in the treatment of moderate-to-severe active ulcerative colitis: design, development and positioning of therapy

The etiology of ulcerative colitis (UC) is complex and involves a host of genetic, epigenetic and environmental factors. Over the last thirty years, signaling pathways like the Janus kinase (JAK) signaling pathway have been implicated in its pathogenesis. Pharmacologic blockade of this pathway is av...

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Bibliografski detalji
Izdano u:Clin Exp Gastroenterol
Glavni autori: Tran, Vivy, Shammas, Rania M, Sauk, Jenny S, Padua, David
Format: Artigo
Jezik:Inglês
Izdano: Dove 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6507103/
https://ncbi.nlm.nih.gov/pubmed/31118734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CEG.S150908
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