Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes

PfEMP1 (erythrocyte membrane protein 1) adhesins play a pivotal role in the pathophysiology of falciparum malaria, by mediating sequestration of Plasmodium falciparum-infected erythrocytes in the microvasculature. PfEMP1 variants are expressed by var genes and are presented on membrane elevations, t...

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Publicat a:Commun Biol
Autors principals: Sanchez, Cecilia P., Karathanasis, Christos, Sanchez, Rodrigo, Cyrklaff, Marek, Jäger, Julia, Buchholz, Bernd, Schwarz, Ulrich S., Heilemann, Mike, Lanzer, Michael
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506540/
https://ncbi.nlm.nih.gov/pubmed/31098405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0429-z
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