Transcriptional Basis for Rhythmic Control of Hunger and Metabolism within the AgRP Neuron

The alignment of fasting and feeding with the sleep/ wake cycle is coordinated by hypothalamic neurons, though the underlying molecular programs remain incompletely understood. Here, we demonstrate that the clock transcription pathway maximizes eating during wakefulness and glucose production during...

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Bibliografiske detaljer
Udgivet i:Cell Metab
Main Authors: Cedernaes, Jonathan, Huang, Wenyu, Ramsey, Kathryn Moynihan, Waldeck, Nathan, Cheng, Lei, Marcheva, Biliana, Omura, Chiaki, Kobayashi, Yumiko, Peek, Clara Bien, Levine, Daniel C., Dhir, Ravindra, Awatramani, Raj, Bradfield, Christopher A., Wang, Xiaozhong A., Takahashi, Joseph S., Mokadem, Mohamad, Ahima, Rexford S., Bass, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506361/
https://ncbi.nlm.nih.gov/pubmed/30827863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.01.023
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