SETDB1-dependent heterochromatin stimulates alternative lengthening of telomeres

Alternative lengthening of telomeres, or ALT, is a recombination-based process that maintains telomeres to render some cancer cells immortal. The prevailing view is that ALT is inhibited by heterochromatin because heterochromatin prevents recombination. To test this model, we used telomere-specific...

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Detaylı Bibliyografya
Yayımlandı:Sci Adv
Asıl Yazarlar: Gauchier, Mathilde, Kan, Sophie, Barral, Amandine, Sauzet, Sandrine, Agirre, Eneritz, Bonnell, Erin, Saksouk, Nehmé, Barth, Teresa K., Ide, Satoru, Urbach, Serge, Wellinger, Raymund J., Luco, Reini F., Imhof, Axel, Déjardin, Jérôme
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Association for the Advancement of Science 2019
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506250/
https://ncbi.nlm.nih.gov/pubmed/31086817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aav3673
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