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Neuronal deletion of Pten results in cerebellar motor learning dysfunction and alterations in intracellular signaling

The purpose of this investigation was to examine cerebellar levels of several molecular signaling pathways, including PI3K/AKT/mTOR signaling and markers of neuronal migration, following loss of the Pten (phosphatase and tensin homolog) gene in a subset of neurons, as well as the accompanying behavi...

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Detalhes bibliográficos
Publicado no:Neuroreport
Main Authors: Nolan, Suzanne O., Jefferson, Taylor S., Reynolds, Conner D., Smith, Gregory D., Holley, Andrew J., Hodges, Samantha L., Lugo, Joaquin N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506221/
https://ncbi.nlm.nih.gov/pubmed/30920436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0000000000001241
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