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Structure of the RecQ C-terminal Domain of Human Bloom Syndrome Protein
Bloom syndrome is a rare genetic disorder characterized by genomic instability and cancer predisposition. The disease is caused by mutations of the Bloom syndrome protein (BLM). Here we report the crystal structure of a RecQ C-terminal (RQC) domain from human BLM. The structure reveals three novel f...
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| Publicado no: | Sci Rep |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6505963/ https://ncbi.nlm.nih.gov/pubmed/24257077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03294 |
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