Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation

Clonal hematopoiesis of indeterminate potential (CHIP) is a recently identified process where older patients accumulate distinct subclones defined by recurring somatic mutations in hematopoietic stem cells. CHIP’s implications for stem cell transplantation have been harder to identify due to the hig...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Park, Derek S., Akuffo, Afua A., Muench, David E., Grimes, H. Leighton, Epling-Burnette, Pearlie K., Maini, Philip K., Anderson, Alexander R. A., Bonsall, Michael B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505959/
https://ncbi.nlm.nih.gov/pubmed/31026273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006913
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