Distinguishing between genotoxic and non-genotoxic hepatocarcinogens by gene expression profiling and bioinformatic pathway analysis

A rapid and sensitive method to determine the characteristics of carcinogens is needed. In this study, we used a microarray-based genomics approach, with a short-term in vivo model, in combination with insights from statistical and mechanistic analyses to determine the characteristics of carcinogens...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Lee, Seul Ji, Yum, Young Na, Kim, Sang Cheol, Kim, Yuneung, Lim, Johan, Lee, Won Jun, Koo, Kyung Hye, Kim, Joo Hwan, Kim, Jee Eun, Lee, Woo Sun, Sohn, Soojung, Park, Sue Nie, Park, Jeong Hill, Lee, Jeongmi, Kwon, Sung Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505678/
https://ncbi.nlm.nih.gov/pubmed/24089152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02783
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