Distinguishing between genotoxic and non-genotoxic hepatocarcinogens by gene expression profiling and bioinformatic pathway analysis

A rapid and sensitive method to determine the characteristics of carcinogens is needed. In this study, we used a microarray-based genomics approach, with a short-term in vivo model, in combination with insights from statistical and mechanistic analyses to determine the characteristics of carcinogens...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Lee, Seul Ji, Yum, Young Na, Kim, Sang Cheol, Kim, Yuneung, Lim, Johan, Lee, Won Jun, Koo, Kyung Hye, Kim, Joo Hwan, Kim, Jee Eun, Lee, Woo Sun, Sohn, Soojung, Park, Sue Nie, Park, Jeong Hill, Lee, Jeongmi, Kwon, Sung Won
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505678/
https://ncbi.nlm.nih.gov/pubmed/24089152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02783
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