Live pigs produced from genome edited zygotes

Transcription activator-like effector nuclease (TALEN) and zinc finger nuclease (ZFN) genome editing technology enables site directed engineering of the genome. Here we demonstrate for the first time that both TALEN and ZFN injected directly into pig zygotes can produce live genome edited pigs. Mono...

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Pubblicato in:Sci Rep
Autori principali: Lillico, Simon G., Proudfoot, Chris, Carlson, Daniel F., Stverakova, Dana, Neil, Claire, Blain, Carol, King, Tim J., Ritchie, William A., Tan, Wenfang, Mileham, Alan J., McLaren, David G., Fahrenkrug, Scott C., Whitelaw, C. Bruce A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505673/
https://ncbi.nlm.nih.gov/pubmed/24108318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02847
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