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Moderate maternal folic acid supplementation ameliorates adverse embryonic and epigenetic outcomes associated with assisted reproduction in a mouse model

STUDY QUESTION: Could clinically-relevant moderate and/or high dose maternal folic acid supplementation prevent aberrant developmental and epigenetic outcomes associated with assisted reproductive technologies (ART)? SUMMARY ANSWER: Our results demonstrate dose-dependent and sex-specific effects of...

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Detalhes bibliográficos
Publicado no:Hum Reprod
Main Authors: Rahimi, Sophia, Martel, Josée, Karahan, Gurbet, Angle, Camille, Behan, Nathalie A, Chan, Donovan, MacFarlane, Amanda J, Trasler, Jacquetta M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505447/
https://ncbi.nlm.nih.gov/pubmed/30989206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/humrep/dez036
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