Homeostatic scaling of active zone scaffolds maintains global synaptic strength

Synaptic terminals grow and retract throughout life, yet synaptic strength is maintained within stable physiological ranges. To study this process, we investigated Drosophila endophilin (endo) mutants. Although active zone (AZ) number is doubled in endo mutants, a compensatory reduction in their siz...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Goel, Pragya, Dufour Bergeron, Dominique, Böhme, Mathias A., Nunnelly, Luke, Lehmann, Martin, Buser, Christopher, Walter, Alexander M., Sigrist, Stephan J., Dickman, Dion
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2019
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504899/
https://ncbi.nlm.nih.gov/pubmed/30914419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807165
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