Homeostatic scaling of active zone scaffolds maintains global synaptic strength

Synaptic terminals grow and retract throughout life, yet synaptic strength is maintained within stable physiological ranges. To study this process, we investigated Drosophila endophilin (endo) mutants. Although active zone (AZ) number is doubled in endo mutants, a compensatory reduction in their siz...

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Bibliografske podrobnosti
izdano v:J Cell Biol
Main Authors: Goel, Pragya, Dufour Bergeron, Dominique, Böhme, Mathias A., Nunnelly, Luke, Lehmann, Martin, Buser, Christopher, Walter, Alexander M., Sigrist, Stephan J., Dickman, Dion
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2019
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504899/
https://ncbi.nlm.nih.gov/pubmed/30914419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807165
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