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Homeostatic scaling of active zone scaffolds maintains global synaptic strength

Synaptic terminals grow and retract throughout life, yet synaptic strength is maintained within stable physiological ranges. To study this process, we investigated Drosophila endophilin (endo) mutants. Although active zone (AZ) number is doubled in endo mutants, a compensatory reduction in their siz...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Goel, Pragya, Dufour Bergeron, Dominique, Böhme, Mathias A., Nunnelly, Luke, Lehmann, Martin, Buser, Christopher, Walter, Alexander M., Sigrist, Stephan J., Dickman, Dion
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504899/
https://ncbi.nlm.nih.gov/pubmed/30914419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201807165
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