MiR-20a-5p regulates gemcitabine chemosensitivity by targeting RRM2 in pancreatic cancer cells and serves as a predictor for gemcitabine-based chemotherapy

Ribonucleotide reductase subunit M2 (RRM2) acts as an important gemcitabine resistance-related gene in pancreatic cancer (PC). Here, we aimed to investigate the potential microRNA that regulates gemcitabine chemosensitivity by targeting RRM2 and explores the clinical significance of candidate miRNA...

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Bibliographic Details
Published in:Biosci Rep
Main Authors: Lu, Huimin, Lu, Shan, Yang, Dujiang, Zhang, Ling, Ye, Jun, Li, Mao, Hu, Weiming
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504660/
https://ncbi.nlm.nih.gov/pubmed/30777929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20181374
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